2023
- Dopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task
Elise Bousseyrol, Steve Didienne, Samir Takillah, Clement Solié, Maxime Come, Tarek Ahmed Yahia, Sarah Mondoloni, Eléonore Vicq, Ludovic Tricoire, Alexandre Mourot, Jérémie Naudé, Philippe Faure
Cell Report Volume 42, Issue 5, 112523, May 30, 2023.
- Impact of the gut microbiome on nicotine’s motivational effects and glial cells in the ventral tegmental area in male mice
Alina Lakosa, Anaïs Rahimian, Flavio Tomasi, Fabio Marti, Lauren M. Reynolds, Léa Tochon, Vincent David, Anne Danckaert, Candice Canonne, Sylvana Tahraoui, Fabrice de Chaumont, Benoît Forget, Uwe Maskos, Morgane Besson
Neuropsychopharmacology (2023), 17/03/203, https://doi.org/10.1038/s41386-023-01563-x
2022
- SWI/SNF chromatin remodeler complex within the reward pathway is required for behavioral adaptations to stress
Abdallah Zayed, Camille Baranowski, Anne-Claire Compagnion, Cecile Vernochet, Samah Karaki, Romain Durand-de Cuttoli, Estefani Saint-Jour, Soumee Bhattacharya, Fabio Marti, Peter Vanhoutte, Moshe Yaniv, Philippe Faure, Jacques Barik, Laurence Amar, Francois Tronche, Sébastien Parnaudeau
Nature Communications volume 13, Article number : 1807 (2022), https://doi.org/10.1038/s41467-022-29380-8
- Social determinants of inter-individual variability and vulnerability: The role of dopamine.
Philippe Faure, Sophie L Fayad, Clément Solié, Lauren M Reynolds
Frontiers in Behavioral Neuroscience, 16, Article 836343, https://doi.org/10.3389/fnbeh.2022.836343
2021
- Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice
Dongelmans M, Durand-de Cuttoli R, Nguyen C, Come M, Duranté EK, Lemoine D, Brito R, Ahmed Yahia T, Mondoloni S, Didienne S, Bousseyrol E, Hannesse B, Reynolds LM, Torquet N, Dalkara D,Marti F, Mourot A, Naudé J , Faure P
Nature Communications volume 12, Article number : 6945 (2021), https://doi.org/10.1038/s41467-021-27268-7
- Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.
Nguyen C, Mondoloni S, Le Borgne T, Centeno I, Come M, Jehl J, Solié C, Reynolds LM, Durand-de Cuttoli R, Tolu S, Valverde S, Didienne S, Hannesse B, Fiancette JF, Pons S, Maskos U, Deroche-Gamonet V, Dalkara D, Hardelin JP, Mourot A, Marti F, Faure P.
Neuron. 2021 Jun 30:S0896-6273(21)00428-1. doi: 10.1016/j.neuron.2021.06.013. Epub ahead of print. PMID: 34242565.
- Loss of floor plate Netrin-1 impairs midline crossing of corticospinal axons and leads to mirror movements.
Pourchet O, Morel MP, Welniarz Q, Sarrazin N, Marti F, Heck N, Galléa C, Doulazmi M, Roig Puiggros S, Moreno-Bravo JA, Vidailhet M, Trembleau A, Faure P, Chédotal A, Roze E, Dusart I.
Cell Rep. 2021 Jan 19;34(3):108654. doi: 10.1016/j.celrep.2020.108654.
2020
- Morozova E., Faure P., Gutkin B., Lapish C., Kuznetsov A.
Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine.
eNeuro. 2020 Jul-Aug. [DOI]. - Lemoine D., Mondoloni S., Tange J., Lambolez B., Faure P., Taly A., Tricoire L., Mourot A.
Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology.
eLife 2020 [DOI]. - Durand-de Cuttoli R., Chauhan P. S., Pétriz Reyes A., Faure P., Mourot A., Ellis-Davies G. C. R.
Optofluidic Control of Rodent Learning Using Cloaked Caged Glutamate.
PNAS 2020. [DOI]. - Berland C., Montalban E., Perrin E., Di Miceli M., Nakamura Y., Martinat M., Sullivan M., Davis X. S., Shenasa M. A., Martin C., Tolu S., Marti F., Caille S., Castel J., Perez S., Salinas C. G., Morel C., Hecksher-Sørensen J., Cador M., Fioramonti X., Tschöp M. H., Layé S., Venance L., Faure P., Hnasko T. S., Small D. M., Gangarossa G., Luquet S. H.
Circulating Triglycerides Gate Dopamine-Associated Behaviors Through DRD2-Expressing Neurons.
Cell Metab 2020 Mar 3. [DOI]. - Belkaid M., Bousseyrol E., .Durand-de Cuttoli R., Dongelmans M., Duranté E.K., Ahmed Yahia T., Didienne S., Hanesse B., Come M., Mourot A., Naudé J, Sigaud O., Faure P.
Mice adaptively generate choice variability in a deterministic task.
Communications Biology 2020. [DOI].
2019
- Mondoloni S., Durand-de Cuttoli R., Mourot A.
Cell-Specific Neuropharmacology
Trends in Pharmacological Sciences 2019 August. [DOI]. - Paoletti P., Ellis-Davis G. C. R., Mourot A.
Optical control of neuronal ion channels and receptors
Nature Reviews Neuroscience 2019 July. [DOI]. - de Chaumont F.*, Ey E.*, Torquet N., Lagache T., Dallongeville S., Imbert A., Legou T., Le Sourd A.-M., Faure P.*, Bourgeron T.*, Olivo-Marin J.-M.*
Real-time analysos of the behaviour of groups of mice via depth-sensing camera and machine learning
Nature biomedical engineering 2019 May. [DOI].
2018
- Lassus B., Naudé J., Faure P., Guedin D., Von Boxberg Y., Mannoury la Cour C., Millan M.-J., Peyrin J.-M.
Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips.
Scientific Reports 2018 Nov 29;8(1):17461. [Abstract]. - Nilsson S. R. O., Heath C. J., Takillah S., Didienne S., Fejgin K., Nielsen V., Nielsen J., Saksida L. M., Mariani J., Faure P., Didriksen M., Robbins T. W., Bussey T. J., Mar A. C.
Continuous performance test impairment in a 22q11.2 microdeletion mouse model: improvement by amphetamine.
Translational Psychiatry 8:247 (2018). [DOI] - Fernandez S. P., Broussot L., Marti F., Contesse T., Mouska X., Soiza-Reilly M., Marie H., Faure P., Barik J.
Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors.
Nature Communications volume 9, Article number: 4449 (2018). [DOI] - Forget B., Scholze P., Langa F., Morel C., Pons S., Mondoloni S., Besson M., Durand-de Cuttoli R., Hay A., Tricoire L., Lambolez B., Mourot A., Faure P., Maskos U.
A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats.
Current Biology 28, 1–10, October 22, 2018. [DOI] - Ey, E., Torquet, N., de Chaumont, F., Lévi-Strauss, J., Ferhat, A., Le Sourd, A.-M., Boeckers, T. M., and Bourgeron, T.
Shank2 mutant mice display hyperactivity insensitive to methylphenidate and reduced flexibility in social motivation, but normal social recognition.
Front. Mol. Neurosci. 2018 11, 1–9. doi:10.3389/fnmol.2018.00365. [DOI] - Durand-de Cuttoli R.*, Mondoloni S.*, Marti F., Lemoine D., Nguyen C., Naudé J., d’Izarny-Gargas T., Pons S., Maskos U., Trauner D., Kramer R.H., Faure P.#, Mourot A.#
Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors.
Elife. 2018 Sep 4;7. pii: e37487. doi: 10.7554/eLife.37487. [Abstract]. - Torquet N., Marti F., Campart C., Tolu S., Nguyen C., Oberto V., Benallaoua M., Naudé J., Didienne S., Debray N., Jezequel S., Le Gouestre L., Hannesse B., Mariani J., Mourot A., Faure P.
Social interactions impact on the dopaminergic system and drive individuality.
Nature Communications. 2018 Jul. doi: 10.1038/s41467-018-05526-5. [Abstract]. - De Backer JF., Monlezun S., Detraux B., Gazan A., Vanopdenbosch L., Cheron J., Cannazza G., Valverde S., Cantacorps L., Nassar M., Venance L., Valverde O., Faure P., Zoli M., De Backer O., Gall D., Schiffmann S.N., de Kerchove d’Exaerde A.
Deletion of Maged1 in mice abolishes locomotor and reinforcing effects of cocaine.
EMBO Reports. 2018 Jul 12. doi: 10.15252/embr.201745089. [Abstract]. - Hay Y.A., Naudé J., Faure P., Lambolez B.
Target Interneuron Preference in Thalamocortical Pathways Determines the Temporal Structure of Cortical Responses.
Cerebral Cortex. 2018 Jul 27. doi: 10.1093/cercor/bhy148. [Abstract]. - Mourot A., Herold C., Kienzler M.A., Kramer R.H.
Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.
Br J Pharmacol. 2018 Jun;175(12):2296-2311. doi: 10.1111/bph.13923 [Abstract]. - Karsinti E., Piani K., Zerdazi E.H., Maskos U., Faure P., Romo L., Bellivier F., Brousse G., Lépine J.-P., Bloch V., Vorspan F.
Relevance of treated cocaine users’ retrospective memory of first cocaine use.
Psychiatry Research. 2018 March 29. [Abstract]. -
Apazoglou K., Farley S., Gorgievski V., Belzeaux R., Lopez J. P., Grenier J., Ibrahim E. C., El Khoury M.-A., Tse Y. C., Mongredien R., Barbé A., de Macedo C. E. A., Jaworski W., Bochereau A., Orrico A., Isingrini E., Guinaudie C., Mikasova L., Louis F., Gautron G., Groc L., Massaad C., Yildirim F., Vialou V., Dumas S., Marti F., Mechawar N., Morice E., Wong T. P., Caboche J., Turecki G., Giros B., T. Tzavara E. T.
Antidepressive effects of targeting ELK-1 signal transduction.
Nature Medicine 24, 2018, 591-597. doi:10.1038/s41591-018-0011-0 [Abstract].
2017
- Durand-de Cuttoli R., Mondoloni S., Mourot A.
Optically dissecting brain nicotinic receptor function with photo-controllable designer receptors.
Biol Aujourdhui, 2017;211(2):173-188. doi: 10.1051/jbio/2017022. [Abstract]. - Doly S., Quentin E., Eddine R., Tolu S., Fernandez S.P., Bertran-Gonzalez J., Valjent E., Belmer A., Viñals X., Callebert J., Faure P., Meye F.J., Hervé D., Robledo P., Mameli M., Launay J.-M., Maldonado R., Maroteaux L.
Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses.
J Neurosci. 2017 Sep 21. pii: 1354-17. doi: 10.1523/JNEUROSCI.1354-17.2017 [Abstract]. - Takillah S.*, Naudé J.*, Didienne S.*, Decros B., Schenker E., Spedding M., Sebban C., Mourot A., Mariani J. and Faure P.
Acute Stress affects the expression of hippocampal Mu oscillations in an age-dependent manner.
Front. Aging Neurosci. | doi: 10.3389/fnagi.2017.00295 [Article]. - Morel C.*, Fernandez S. P.*, Pantouli F., Meye F. J., Marti F., Tolu S., Parnaudeau S., Marie H., Tronche F., Maskos U., Moretti M., Gotti C., Han M.-H., Bailey, Mameli A. M., Barik J. and Faure P.
Nicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells’ activity.
Molecular Psychiatry 2017. doi: 10.1038/mp.2017.145 [Article]. - Benamer N.*, Marti F.*, Lujan R., Hepp R., Aubier T. G., Dupin A. A. M., Frébourg G., Pons S., Maskos U., Faure P., Hay Y. A., Lambolez B. and Tricoire L.
GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons.
Molecular Psychiatry 2017 Jul 11. doi: 10.1038/mp.2017.137 [Article]. - Tolu S., Marti F., Morel C., Perrier C., Torquet N., Pons S., de Beaurepaire R., Faure P. Nicotine enhances alcohol intake and dopaminergic responses through β2* and β4* nicotinic acetylcholine receptors. Scientific Report [Article].
- Artigas F., Schenker E., Celada P., Spedding M., Lladó-Pelfort L., Jurado N., Núñez M., Santana N., Troyano-Rodriguez E., Riga MS., van den Munkhof H., Castañé A., Shaban H., Jay TM., Tripathi A., Godsil BP., Sebban C., Mariani J., Faure P., Takkilah S., Hughes ZA., Siok CJ., Hajos M., Wicke K., Gass N., Weber-Fahr W., Sartorius A., Becker R., Didriksen M., Bastlund JF., Tricklebank M., Risterucci C., Meyer-Lindenberg A., Schwarz AJ. (2017). Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS. Nature reviews Drug discovery, 16(1), pp.1–2. [Abstract]
2016
- Lemoine D., Durand-de Cuttoli R., Mourot A. (2016) Optogenetic Control of Mammalian Ion Channels with Chemical Photoswitches. Methods Mol Biol.;1408:177-93. doi: 10.1007/978-1-4939-3512-3_12. [Abstract]
- Besson M., Guiducc S., Granon S., Guilloux J.-P., Guiard B., Repérant C., Faure P., Pons S., Cannazza G., Zoli M., Gardier A., Maskos U. (2016). Alterations in alpha5* nicotinic acetylcholine receptors result in midbrain- and hippocampus-dependent behavioural and neural impairments. Psychopharmacology (Berl), 233(18), pp.3297–3314. [Abstract]
- Royet J.-P., Meunier D., Torquet N., Mouly A.-M., Jiang T.
The Neural Bases of Disgust for Cheese: An fMRI Study
Front. Hum. Neurosci. 10:511. doi: 10.3389/fnhum.2016.00511 (2016) [Abstract] F1000 - Torquet N., De Chaumont F., Faure P., Bourgeron T., Ey E.
mouseTube – a database to collaboratively unravel mouse ultrasonic communication
F1000Research, 5:2332, doi: 10.12688/f1000research.9439.1 (2016). [Abstract] - Ferhat A.-T., Torquet N., Le Sourd A.-M., de Chaumont F., Olivo-Marin J.-C., Faure P., Bourgeron T., Ey E.
Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication.
J. Vis. Exp. (112), e53871, doi:10.3791/53871 (2016). [Abstract] - Harrington L., Viñals X., Herrera-Solís A., Flores A., Morel C., Tolu S., Faure P., Maldonado R., Maskos U., Robledo P.
Role of β4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice.
Neuropsychopharmacology, 2016 Jun;41(7):1790-802. doi: 10.1038/npp.2015.346. Epub 2015 Nov 20. [Abstract] - Isingrini E., Perret L., Rainer Q., Amilhon B., Guma E., Tanti A., Martin G., Robinson J., Moquin L., Marti F., Mechawar N., Williams S., Gratton A., Giros B.
Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.
Nat Neurosci. 2016 Apr;19(4):560-3. doi: 10.1038/nn.4245. Epub 2016 Feb 15. [Abstract] - Naudé J., Tolu S., Dongelmans M., Torquet N., Valverde S., Rodriguez G., Pons S., Maskos U., Mourot A., Marti F., Faure P.
Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.
Nature Neuroscience, january 2016, doi:10.1038/nn.4223. [Abstract] - Faure P. and Mourot A.
Le récepteur Nicotinique
Traité d’addictologie, Ed Reynaud M, Karila L, Amine Benyamina A et Aubin HJ, Médecine Sciences Publications
2015
- Glangetas C., Fois G. R., Jalabert M., Lecca S., Valentinova K., Meye F. J., Diana M., Faure P., Mameli M., Caille S., Georges F.
Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine.
CellReports, November 21, 2015, 1–11. doi:10.1016/j.celrep.2015.10.076. [Abstract] F1000 - Eddine R.*, Valverde S.*, Tolu S., Dautan D., Hay A., Morel C., Cui Y., Lambolez B., Venance L., Marti F., Faure P.
A concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotine
Scientific Reports. 2015 Feb 2;5:8184. doi: 10.1038/srep08184. [Abstract] - Naudé J., Dongelmans M., Faure P.
Nicotinic alteration of decision-making.
Neuropharmacology. 2015 Sep;96(Pt B):244-54. doi: 10.1016/j.neuropharm.2014.11.021. Epub 2014 Dec 9. [Abstract] - Oster, A., Faure, P. & Gutkin, B. S. Mechanisms for multiple activity modes of VTA dopamine neurons. Frontiers in Computational Neuroscience. 2015 Jul 28;9:95. doi: 10.3389/fncom.2015.00095. eCollection 2015. [Abstract]
- Sakae D.Y.*, Marti F.*, Lecca S.*, Vorspan F., Martín-García E., Morel L.J., Henrion A., Gutiérrez-Cuesta J., Besnard A., Heck N., Herzog E., Bolte S., Prado V.F., Prado M.A., Bellivier F., Eap C.B., Crettol S., Vanhoutte P., Caboche J., Gratton A., Moquin L., Giros B., Maldonado R., Daumas S., Mameli M., Jamain S., El Mestikawy S. The absence of VGLUT3 predisposes to cocaine abuse by increasing dopamine and glutamate signaling in the nucleus accumbens. Molecular Psychiatry. 2015 Aug 4. doi: 10.1038/mp.2015.104. [Abstract]
- Faure P. and Lesne A. Estimating Kolmogorov Entropy from Recurrence Plots. Reccurence Quantification Analysis – Theory and Best Practices, Chapter 2. Springer book. 2015. ISBN 978-3-319-07155-8.
2014
- Nomura S., Bouhadana M., Morel C., Faure P., Cauli B., Lambolez B., Hepp R.
Noradrenalin and dopamine receptors both control cAMP-PKA signaling throughout the cerebral cortex.
Front Cell Neurosci. 2014 Aug 21;8:247. doi: 10.3389/fncel.2014.00247. [Abstract] - Torquet N., Aimé P., Messaoudi B., Garcia S., Ey E., Gervais R., Julliard A.K., Ravel N.
Olfactory preference conditioning changes the reward value of reinforced and non-reinforced odors.
Frontiers in Behavioral Neuroscience. doi: 10.3389/fnbeh.2014.00229. Publication Date (Web): July 3, 2014. [Abstract] - Faure P., Tolu S., Valverde S., Naudé J.
The role of nicotinic acetylcholine receptors in regulating Dopamine neuron activity.
Neuroscience, Just Accepted Manuscript. doi: 10.1016/j.neuroscience.2014.05.040. Publication Date (Web): May 29, 2014. [Abstract] - Lin WC., Davenport C.M., Mourot A., Vytla D., Smith C.M., Medeiros K.A., Chambers J.J., Kramer R.H.
Engineering a light-regulated GABAA receptor for optical control of neural inhibition.
ACS Chem. Biol., Just Accepted Manuscript. doi: 10.1021/cb500167u. Publication Date (Web): May 12, 2014. [Abstract] - Morel C.*, Fattore L.*, Pons S., Hay YA., Marti F., Lambolez B., De Biasi M., Lathrop M., Fratta W., Maskos U., Faure P.
Nicotine consumption is regulated by a human polymorphism in dopamine neurons.
Mol Psychiatry. 2014 AUG;19(8):930-6. doi: 10.1038/mp.2013.158. [Abstract]
2013
- Naudé, J., Cessac, B., Berry, H., Delord, B.
Effects of cellular homeostatic intrinsic plasticity on dynamical and computational properties of biological recurrent neural networks.
The Journal of Neuroscience, 33(38), 15032-15043. [Abstract] - Da Re S., Valle, J., Charbonnel N., Beloin C., Latour-Lambert P., Faure P., Turlin E., Le Bouguénec C., Renauld-Mongénie G., Forestier C., Ghigo J.-M.
Identification of Commensal Escherichia coli Genes Involved in Biofilm Resistance to Pathogen Colonization.
PLoS ONE, 8(5), e61628. doi:10.1371/journal.pone.0061628. [Abstract] - Ey E., Torquet N., Le Sourd A.-M., Leblond C. S., Boeckers T. M., Faure P., Bourgeron T.
The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations.
Behav. Brain Res. 2013 Aug 28. [Abstract] - Kramer R.H., Mourot A., Adesnik H.
Optogenetic pharmacology for control of native neuronal signaling proteins.
Nature Neuroscience. 2013 Jun 25;16(7):816-23. doi: 10.1038/nn.3424. [Abstract] - Mourot A., Tochitsky I., Kramer R.H.
Light at the end of the channel: optical manipulation of intrinsic neuronal excitability with chemical photoswitches.
Front Mol Neurosci. 2013;6:5. doi: 10.3389/fnmol.2013.00005. [Abstract] - Mourot A., Fehrentz T., Kramer R.H.
Photochromic potassium channel blockers: design and electrophysiological characterization.
Methods Mol Biol. 2013;995:89-105. doi: 10.1007/978-1-62703-345-9_7. [Abstract] - Barik J., Marti F., Morel C., Fernandez S.P., Lanteri C., Godeheu G., Tassin J.-P., Mombereau C., Faure P., Tronche F.
Chronic stress triggers social aversion via glucocorticoid receptor in dopaminoceptive neurons.
Science.;339(6117):332-5. doi: 10.1126/science.122 [Abstract] F1000 (Perspective in Science, Science daily) - Tolu S.*, Eddine R.*, Marti F.*, David V., Graupner M., Pons S., Baudonnat M., Husson M., Besson M., Reperant C., Zemdegs J., Pagès C., Hay Y.A., Lambolez B., Caboche J., Gutkin B., Gardier A.M., Changeux J.-P., Faure P., Maskos U.
Co-activation of VTA DA and GABA neurons mediates nicotine reinforcement.
Mol Psychiatry. 2012 Jul 3. doi: 10.1038/mp.2012.8 [Abstract] F1000
2012
2011
2010
2009
2008
2007
2006
2005
2004
2003
2002
Mourot A., Kotzyba-Hibert F., Doris E., Goeldner M.
New and convenient synthesis of a tritiated photoactivatable nicotinic agonist: [3H]-AC5.
J. Label. Compd. Radiopharm. 45: 943-53
2001
2000
- Faure P., Kaplan D., Korn H.
Synaptic efficacy and the transmission of complex firing patterns between neurons.
J. Neurophysiol.;84(6):3010-25. [Abstract]