News

12/08/2019 New review in Trends in Pharmacological Sciences:

Sarah Mondoloni, Romain Durand-de Cuttoli and Alexandre Mourot
Cell-Specific Neuropharmacology. 2019 DOI: 10.1016/j.tips.2019.07.007 [DOI].

nrn_sept_cover11/07/2019 New review in Nature Reviews Neuroscience:

Pierre Paoletti, Graham C. R. Ellis-Davies and Alexandre Mourot
Optical control of neuronal ion channels and receptors. NatRevNeuro. 2019 DOI: 10.1038/s41583-019-0197-2 [DOI].

Prix fondation NRJ05/06/2019 Philippe Faure was awarded with the NRJ Fondation price.

13/02/2019 Philippe Faure and Nicolas Torquet were awarded with the La Recherche 2019 price in neuroscience for their work on individuation

Prix La Recherche 2019

Our results, published in August 2018, show that the social environment of mice was a determining factor of their behavioral traits.

19/10/2018 Offres de stages Master 2 en informatique / traitement de données

Nous sommes à la recherche de deux stagiaires en M2.
– Le premier stage portera sur l’implémentation d’un système de tracking vidéo (Live Mouse Tracker) dans des environnements complexes (Souris City). Le stagiaire devra connaître le langage Java afin d’adapter le logiciel de tracking. Des connaissances en électronique pour la réalisation de planchers RFID, ainsi que des connaissances en SQL et python seraient souhaitables pour mener à bien ce stage.
– Le deuxième stage portera sur l’intégration des données de différentes sources en vue de l’automatisation des traitements. Le stagiaire aura pour travail de créer une méthode d’intégration des données SQLite dans des bases MySQL et d’en assurer la cohérence. Le stagiaire devra maîtriser le SQL, les SGBD SQLite et MySQL. Il devra également connaître Python qu’il utilisera pour créer un logiciel de gestion de données. Des connaissances en php/html serait un plus pour la création d’une interface web.
Vous pouvez nous contacter pour toutes questions / candidatures: philippe.faure at upmc.fr et nicolas.torquet at upmc.fr

cover-elife04/09/2018 New article in elife:

Romain Durand-de Cuttoli, Sarah Mondoloni, Fabio Marti, Damien Lemoine, Claire Nguyen, Jérémie Naudé, Thibaut d’Izarny-Gargas, Stéphanie Pons,Uwe Maskos, Dirk Trauner, Richard H Kramer, Philippe Faure, Alexandre Mourot
Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors. elife. 2018 DOI: 10.7554/eLife.37487 [Abstract].

Souriscity06/08/2018 New article in Nature Communications:

Torquet N., Marti F., Campart C., Tolu S., Nguyen C., Oberto V., Benallaoua M., Naudé J., Didienne S., Debray N., Jezequel S., Le Gouestre L., Hannesse B., Mariani J., Mourot A., Faure P.
Social interactions impact on the dopaminergic system and drive individuality. Nature Communications. 2018 Jul. doi: 10.1038/s41467-018-05526-5. [Abstract].

30/01/2018 “Switching sarah_presentation_sorbonne_2off nicotine addiction with light”:  an awesome talk given by our PhD student Sarah Mondoloni during the Sorbonne Université inauguration day.

23/12/souriscity2017 New preprint: Social interactions impact on the dopaminergic system and drive individuality.

Nicolas TorquetFabio Marti, Cynthia Campart, Stefania Tolu, Claire Nguyen, Virginie Oberto, Jérémie Naudé, Steve Didienne, Soizic Jezequel, Laura Le Gouestre, Nicolas Debray, Alexandre Mourot, Jean Mariani, Philippe Faure. ioRxiv [Abstract].

photoswitch13/12/2017 New article in Biologie Aujourd’hui

Durand-de Cuttoli R., Mondoloni S., Mourot A.
Optically dissecting brain nicotinic receptor function with photo-controllable designer receptors.
Biol Aujourdhui. 2017;211(2):173-188. doi: 10.1051/jbio/2017022. Epub 2017 Dec 13. French. [Abstract].

05/10/2017 New article in the Journal of Neuroscience

Doly S., Quentin E., Eddine R., Tolu S., Fernandez S.P., Bertran-Gonzalez J., Valjent E., Belmer A., Viñals X., Callebert J., Faure P., Meye F.J., Hervé D., Robledo P., Mameli M., Launay J.-M., Maldonado R., Maroteaux L.
Serotonin 2B receptors in mesoaccumbens dopamine pathway regulate cocaine responses.
J Neurosci. 2017 Sep 21. pii: 1354-17. doi: 10.1523/JNEUROSCI.1354-17.2017 [Abstract].

02/10/2017 Romain Durand-de Cuttoli dances his PhD

Romain Durand-de Cuttoli, PhD in the team, participates to “Dance your PhD”, a contest organized by Science.

If you want to support Romain, please click on the thumbs up!

27/09/2017 Fabio Marti on TV (TéléMatin – France 2)

See the video.

19/09/2017 New article in the British journal of Pharmacological

Mourot A., Herold C., Kienzler M.A., Kramer R.H.
Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches.
Br J Pharmacol. 2017 [Abstract].

19/09/2017 New article in Frontiers in Aging Neuroscience

Takillah S. , Naudé J., Didienne S., Decros B., Schenker E., Spedding M., Sebban C., Mourot A., Mariani J. and Faure P.
Acute Stress affects the expression of hippocampal Mu oscillations in an age-dependent manner.
Front. Aging Neurosci. 2017 [Article].

15/09/2017 Congratulations to Nicolas, our IgNobel prize winner, for his work on stinky cheese!!!!!!!!!!

MEDICINE PRIZE [FRANCE, UK] — Jean-Pierre Royet, David Meunier, Nicolas Torquet, Anne-Marie Mouly and Tao Jiang, for using advanced brain-scanning technology to measure the extent to which some people are disgusted by cheese.

REFERENCE: “The Neural Bases of Disgust for Cheese: An fMRI Study,” Jean-Pierre Royet, David Meunier, Nicolas Torquet, Anne-Marie Mouly and Tao Jiang, Frontiers in Human Neuroscience, vol. 10, October 2016, article 511.

New article in Molecular Psychiatry

Morel C., Fernandez S. P., Pantouli F., Meye F. J., Marti F., Tolu S., Parnaudeau S., Marie H., Tronche F., Maskos U., Moretti M., Gotti C., Han M.-H., Bailey, Mameli A. M., Barik J. and Faure P.
Nicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells’ activity.
Molecular Psychiatry 2017 [Article].

New article in Molecular Psychiatry

Benamer N., Marti F., Lujan R., Hepp R., Aubier T. G., Dupin A. A. M., Frébourg G., Pons S., Maskos U., Faure P., Hay Y. A., Lambolez B. and Tricoire L.
GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons.
Molecular Psychiatry 2017 [Article].

Participate in our new game!

Go to the game.

New article in Scientific Report

Stefania Tolu, Fabio Marti, Carole Morel, Carole Perrier, Nicolas Torquet, Stephanie Pons, Renaud de Beaurepaire, and Philippe Faure.
Nicotine enhances alcohol intake and dopaminergic responses through β2* and β4* nicotinic acetylcholine receptors.
Scientific Report 2017 [Article].

Congratulations to Dr Alexandre Mourot

Alexandre was awarded the Medisite foundation prize in Neuroscience.

New article in Nature rewiews Drug Discovery

Artigas F., Schenker E., Celada P., Spedding M., Lladó-Pelfort L., Jurado N., Núñez M., Santana N., Troyano-Rodriguez E., Riga MS., van den Munkhof H., Castañé A., Shaban H., Jay TM., Tripathi A., Godsil BP., Sebban C., Mariani J., Faure P., Takkilah S., Hughes ZA., Siok CJ., Hajos M., Wicke K., Gass N., Weber-Fahr W., Sartorius A., Becker R., Didriksen M., Bastlund JF., Tricklebank M., Risterucci C., Meyer-Lindenberg A., Schwarz AJ. (2017). Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS. Nature reviews Drug discovery, 16(1), pp.1–2. [Abstract]

Congratulations to Dr Steve Didienne

Steve successfully defended his PhD on december 2.

New article in Psychopharmacology

Besson M., Guiducc S., Granon S., Guilloux J.-P., Guiard B., Repérant C., Faure P., Pons S., Cannazza G., Zoli M., Gardier A., Maskos U. (2016). Alterations in alpha5* nicotinic acetylcholine receptors result in midbrain- and hippocampus-dependent behavioural and neural impairments. Psychopharmacology (Berl), 233(18), pp.3297–3314. [Abstract]

New article in Frontiers in Human Neuroscience

Royet J.-P., Meunier D., Torquet N., Mouly A.-M., Jiang T.
The Neural Bases of Disgust for Cheese: An fMRI Study
Front. Hum. Neurosci. 10:511. doi: 10.3389/fnhum.2016.00511 (2016) [Abstract]

New article in F1000 research

Torquet N., De Chaumont F., Faure P., Bourgeron T., Ey E.
mouseTube – a database to collaboratively unravel mouse ultrasonic communication
F1000Research, 5:2332, doi: 10.12688/f1000research.9439.1 (2016). [Abstract]

New article in Jove

Ferhat A.-T., Torquet N., Le Sourd A.-M., de Chaumont F., Olivo-Marin J.-C., Faure P., Bourgeron T., Ey E.
Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication.
J. Vis. Exp. (112), e53871, doi:10.3791/53871 (2016). [Abstract]

New article in Nature Neuroscience

Isingrini E., Perret L., Rainer Q., Amilhon B., Guma E., Tanti A., Martin G., Robinson J., Moquin L., Marti F., Mechawar N., Williams S., Gratton A., Giros B.
Resilience to chronic stress is mediated by noradrenergic regulation of dopamine neurons.
Nat Neurosci. 2016 Apr;19(4):560-3. doi: 10.1038/nn.4245. Epub 2016 Feb 15. [Abstract]

New article in Nature Neuroscience

Naudé J., Tolu S., Dongelmans M., Torquet N., Valverde S., Rodriguez G., Pons S., Maskos U., Mourot A., Marti F., Faure P.
Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.
Nature Neuroscience, january 2016, doi:10.1038/nn.4223. [Abstract]

mouseTube online

logo_mousetube_littlemouseTube is an online database allowing scientists to share mouse ultrasonic vocalization audio files. mouseTube allows to sort vocalization recordings by mouse strain, or by a given context within a protocol. mouseTube facilitates the comparison of ultrasonic vocalizations between individuals, strains, contexts… Link to mouseTube.

Here is a short video introduction to mouseTube: