Alexandre Mourot


Alexandre Mourot
Associate researcher (CR1) INSERM
Neuroscience Paris-Seine – IBPS
Equipe Neurophysiologie et Comportement (NPC)
Boite 16, Universite P. et M. Curie,
9 quai St Bernard, 75005, Paris, FRANCE
Tel: +33 1 44 27 39 40
almourot at
CV pdf file

Research interests

  • Optogenetics and optochemical genetics
  • Biophysics and chemical biology of ion channels
  • Molecular and cellular electrophysiology
  • Neurobiology of the central and peripheral nervous system

Main publications

  • Kramer R.H., Mourot A., Adesnik H. (2013) Optogenetic pharmacology for control of native neuronal signaling proteins. Nature Neuroscience. 2013 Jun 25;16(7):816-23. doi: 10.1038/nn.3424. [Abstract]
  • A Mourot*, T Fehrentz*, Y Lefeuvre, CM Smith, C Herold, D Dalkara, D Trauner and RH Kramer (2012) Rapid optical control of nociception with an ion channel photoswitch, Nat. Meth. 9: 396-402. [Abstract] (Covered by the Guardian (UK), the Telegraph (India), dradio (Germany), Pain research forum, Science Daily,, Ars Technica…)
  • I Tochitsky*, M Banghart*, A Mourot, J Yao, B Gaub, RH Kramer, D Trauner (2012) Optochemical Control of Genetically Engineered Neuronal Nicotinic Acetylcholine Receptors, Nat. Chem. 4: 105–111. [Abstract] F1000 (News and Views Nature Chemistry)
  • L Donato, A Mourot, CM Davenport, C Herbivo, F Bolze, JF Nicoud, RH Kramer, M Goeldner and A Specht (2012) Water-soluble donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)-propyl series for highly efficient two-photon uncaging of the neurotransmitter GABA at 800 nm, Angew. Chem. Intl. Ed. 51:1840-3. [Abstract]
  • MR Banghart*, A Mourot*, D Fortin, J Yao, RH Kramer and D Trauner (2009) Photochromic blockers of voltage-gated potassium channels, Angew. Chem. Intl. Ed. 48: 9097-101. [Abstract] (Covered by C&EN; Selected as “Hot paper” by Angew. Chem. Intl. Ed.)